GO:0043565 |
6 |
sequence-specific DNA binding |
F |
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
GO:0090282 |
7 |
positive regulation of transcription involved in G2/M transition of mitotic cell cycle |
P |
Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle. |
GO:0005634 |
5 |
nucleus |
C |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
GO:0006355 |
6 |
regulation of transcription, DNA-templated |
P |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
GO:0001077 |
6 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding |
F |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter. |
GO:0003677 |
5 |
DNA binding |
F |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0000978 |
10 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
F |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II. |
GO:0001078 |
6 |
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding |
F |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
GO:0005829 |
5 |
cytosol |
C |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
GO:0003688 |
8 |
DNA replication origin binding |
F |
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. |