The 9 common GO terms of the PCTFP (Hir1-Hir3)

GO ID GO Level GO Term GO Aspect GO Term Definition
GO:0000417 4 HIR complex C A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.
GO:0006336 7 DNA replication-independent nucleosome assembly P The formation of nucleosomes outside the context of DNA replication.
GO:0005634 5 nucleus C A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0003714 5 transcription corepressor activity F Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
GO:0031491 5 nucleosome binding F Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
GO:0006355 6 regulation of transcription, DNA-templated P Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0006351 6 transcription, DNA-templated P The cellular synthesis of RNA on a template of DNA.
GO:0003677 5 DNA binding F Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0006368 8 transcription elongation from RNA polymerase II promoter P The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.