| GO:0006355 |
6 |
regulation of transcription, DNA-templated |
P |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| GO:0005634 |
5 |
nucleus |
C |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| GO:0003714 |
5 |
transcription corepressor activity |
F |
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery. |
| GO:0006351 |
6 |
transcription, DNA-templated |
P |
The cellular synthesis of RNA on a template of DNA. |