GO:0043565 |
6 |
sequence-specific DNA binding |
F |
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
GO:0006338 |
7 |
chromatin remodeling |
P |
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. |
GO:0005829 |
5 |
cytosol |
C |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
GO:0006355 |
6 |
regulation of transcription, DNA-templated |
P |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
GO:0003677 |
5 |
DNA binding |
F |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0000978 |
10 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
F |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II. |
GO:0005634 |
5 |
nucleus |
C |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |