GO:0005737 |
4 |
cytoplasm |
C |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
GO:0005634 |
5 |
nucleus |
C |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
GO:0016020 |
2 |
membrane |
C |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
GO:0001077 |
6 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding |
F |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter. |
GO:0045944 |
7 |
positive regulation of transcription from RNA polymerase II promoter |
P |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
GO:0005886 |
3 |
plasma membrane |
C |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
GO:0003677 |
5 |
DNA binding |
F |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0000978 |
10 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
F |
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II. |
GO:0046872 |
5 |
metal ion binding |
F |
Interacting selectively and non-covalently with any metal ion. |