The 6 common GO terms of the PCTFP (Ume6-Sin3)

GO ID GO Level GO Term GO Aspect GO Term Definition
GO:0033698 6 Rpd3L complex C A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).
GO:0005634 5 nucleus C A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0070210 5 Rpd3L-Expanded complex C A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.
GO:0006355 6 regulation of transcription, DNA-templated P Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0006351 6 transcription, DNA-templated P The cellular synthesis of RNA on a template of DNA.
GO:0016568 6 chromatin modification P The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure.