| Experimental System | Publication | Throughput | 
|---|---|---|
| Two-hybrid | Rothermel BA (1997) | Low Throughput | 
| Affinity Capture-Western | Sekito T (2000) | Low Throughput | 
| Reconstituted Complex | Jia Y (1997) | Low Throughput | 
| Affinity Capture-MS | Krogan NJ (2006) | High Throughput | 
| Affinity Capture-MS | Breitkreutz A (2010) | High Throughput | 
| Experimental System | Publication | Throughput | 
|---|---|---|
| Positive Genetic | Collins SR (2007) | High Throughput | 
| Positive Genetic | Fiedler D (2009) | High Throughput | 
| Positive Genetic | Aguilar PS (2010) | High Throughput | 
| Positive Genetic | Bandyopadhyay S (2010) | High Throughput | 
| Positive Genetic | Hoppins S (2011) | High Throughput |