The 32 papers which experimentally study the biological roles of both TFs of the PCTFP (Aft1-Mac1)
Qi J, et al. (2012) Metal-sensing transcription factors Mac1p and Aft1p coordinately regulate vacuolar copper transporter CTR2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 423(2):424-8
Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
van Bakel H, et al. (2005) Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol Genomics 22(3):356-67
Ruotolo R, et al. (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67
Schroder I, et al. (2003) Microbial ferric iron reductases. FEMS Microbiol Rev 27(2-3):427-47
Achcar F, et al. (2011) A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress. BMC Syst Biol 5(1):51
Minear S, et al. (2011) Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell 10(11):1574-81
Andrews NC, et al. (1999) Iron transport across biologic membranes. Nutr Rev 57(4):114-23
Lesuisse E, et al. (1998) Siderophore-mediated iron uptake in Saccharomyces cerevisiae: the SIT1 gene encodes a ferrioxamine B permease that belongs to the major facilitator superfamily. Microbiology 144 ( Pt 12)():3455-62
Kyoda K, et al. (2004) DBRF-MEGN method: an algorithm for deducing minimum equivalent gene networks from large-scale gene expression profiles of gene deletion mutants. Bioinformatics 20(16):2662-75
Lai WK and Buck MJ (2013) An integrative approach to understanding the combinatorial histone code at functional elements. Bioinformatics 29(18):2231-7
De Silva DM, et al. (1996) Molecular mechanisms of iron uptake in eukaryotes. Physiol Rev 76(1):31-47
North M, et al. (2011) Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast. PLoS One 6(8):e24205
Pierre JL, et al. (2002) Chemistry for an essential biological process: the reduction of ferric iron. Biometals 15(4):341-6
Martins LJ, et al. (1998) Metalloregulation of FRE1 and FRE2 homologs in Saccharomyces cerevisiae. J Biol Chem 273(37):23716-21
Viau CM, et al. (2012) Enhanced resistance of yeast mutants deficient in low-affinity iron and zinc transporters to stannous-induced toxicity. Chemosphere 86(5):477-84
Dancis A (1998) Genetic analysis of iron uptake in the yeast Saccharomyces cerevisiae. J Pediatr 132(3 Pt 2):S24-9
Jothi R, et al. (2009) Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture. Mol Syst Biol 5:294
Cyert MS and Philpott CC (2013) Regulation of cation balance in Saccharomyces cerevisiae. Genetics 193(3):677-713
Homann OR, et al. (2009) A phenotypic profile of the Candida albicans regulatory network. PLoS Genet 5(12):e1000783
Bleackley MR and MacGillivray RT (2011) Transition metal homeostasis: from yeast to human disease. Biometals 24(5):785-809
Ehrensberger KM and Bird AJ (2011) Hammering out details: regulating metal levels in eukaryotes. Trends Biochem Sci 36(10):524-31
Eide DJ (1998) The molecular biology of metal ion transport in Saccharomyces cerevisiae. Annu Rev Nutr 18():441-69
Georgatsou E and Alexandraki D (1999) Regulated expression of the Saccharomyces cerevisiae Fre1p/Fre2p Fe/Cu reductase related genes. Yeast 15(7):573-84
Foster AW, et al. (2014) A chemical potentiator of copper-accumulation used to investigate the iron-regulons of Saccharomyces cerevisiae. Mol Microbiol 93(2):317-30
Crisp RJ, et al. (2006) Recruitment of Tup1p and Cti6p regulates heme-deficient expression of Aft1p target genes. EMBO J 25(3):512-21
Luscombe NM, et al. (2004) Genomic analysis of regulatory network dynamics reveals large topological changes. Nature 431(7006):308-12
Rutherford JC and Bird AJ (2004) Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells. Eukaryot Cell 3(1):1-13
Babbitt GA (2010) Relaxed selection against accidental binding of transcription factors with conserved chromatin contexts. Gene 466(1-2):43-8
Arino J (2010) Integrative Responses to High pH Stress in S. cerevisiae. OMICS 14(5):517-23
De Freitas JM, et al. (2004) Exploratory and confirmatory gene expression profiling of mac1Delta. J Biol Chem 279(6):4450-8