The 61 papers which experimentally study the biological roles of both TFs of the PCTFP (Hir1-Hir2)
Verreault A (2003) Histone deposition at the replication fork: a matter of urgency. Mol Cell 11(2):283-4
Hart CE, et al. (2006) Connectivity in the yeast cell cycle transcription network: inferences from neural networks. PLoS Comput Biol 2(12):e169
Verreault A (2000) De novo nucleosome assembly: new pieces in an old puzzle. Genes Dev 14(12):1430-8
Nourani A, et al. (2006) Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae. Mol Cell Biol 26(4):1496-509
Harkness TA, et al. (2005) Contribution of CAF-I to anaphase-promoting-complex-mediated mitotic chromatin assembly in Saccharomyces cerevisiae. Eukaryot Cell 4(4):673-84
Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Verzijlbergen KF, et al. (2011) A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover. PLoS Genet 7(10):e1002284
Silva AC, et al. (2012) The replication-independent histone H3-H4 chaperones HIR, ASF1, and RTT106 co-operate to maintain promoter fidelity. J Biol Chem 287(3):1709-18
Green EM, et al. (2005) Replication-independent histone deposition by the HIR complex and Asf1. Curr Biol 15(22):2044-9
Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52
On T, et al. (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89
Hall C, et al. (2001) HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression. Mol Cell Biol 21(5):1854-65
Kirov N, et al. (1998) Isolation and characterization of a new gene encoding a member of the HIRA family of proteins from Drosophila melanogaster. Gene 212(2):323-32
Feser J, et al. (2010) Elevated histone expression promotes life span extension. Mol Cell 39(5):724-35
Ahmad A, et al. (2004) WD dipeptide motifs and LXXLL motif of chicken HIRA are essential for interactions with the p48 subunit of chromatin assembly factor-1 and histone deacetylase-2 in vitro and in vivo. Gene 342(1):125-36
Cheung V, et al. (2008) Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome. PLoS Biol 6(11):e277
Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83
Vishnoi N, et al. (2011) Separation-of-function mutation in HPC2, a member of the HIR complex in S. cerevisiae, results in derepression of the histone genes but does not confer cryptic TATA phenotypes. Biochim Biophys Acta 1809(10):557-66
Formosa T, et al. (2002) Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure. Genetics 162(4):1557-71
Nelson DM, et al. (2002) Coupling of DNA synthesis and histone synthesis in S phase independent of cyclin/cdk2 activity. Mol Cell Biol 22(21):7459-72
Gradolatto A, et al. (2008) Saccharomyces cerevisiae Yta7 Regulates Histone Gene Expression. Genetics 179(1):291-304
Magnaghi P, et al. (1998) HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3. Nat Genet 20(1):74-7
Neumuller RA, et al. (2013) Conserved regulators of nucleolar size revealed by global phenotypic analyses. Sci Signal 6(289):ra70
Spector MS and Osley MA (1993) The HIR4-1 mutation defines a new class of histone regulatory genes in Saccharomyces cerevisiae. Genetics 135(1):25-34
Smolle M, et al. (2012) Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange. Nat Struct Mol Biol 19(9):884-92
Llevadot R, et al. (1998) Cloning, chromosome mapping and expression analysis of the HIRA gene from Drosophila melanogaster. Biochem Biophys Res Commun 249(2):486-91
Wu WS, et al. (2006) Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle. BMC Bioinformatics 7(1):421
Song Y, et al. (2013) Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3. Nucleic Acids Res 41(10):5199-209
Osley MA and Lycan D (1987) Trans-acting regulatory mutations that alter transcription of Saccharomyces cerevisiae histone genes. Mol Cell Biol 7(12):4204-10
McInerny CJ (2011) Cell cycle regulated gene expression in yeasts. Adv Genet 73():51-85
Gaytan BD, et al. (2013) Functional genomics indicates yeast requires Golgi/ER transport, chromatin remodeling, and DNA repair for low dose DMSO tolerance. Front Genet 4():154
Lamour V, et al. (1995) A human homolog of the S. cerevisiae HIR1 and HIR2 transcriptional repressors cloned from the DiGeorge syndrome critical region. Hum Mol Genet 4(5):791-9
Kim HJ, et al. (2009) Potential role of the histone chaperone, CAF-1, in transcription. BMB Rep 42(4):227-31
Kainth P and Andrews B (2010) Illuminating transcription pathways using fluorescent reporter genes and yeast functional genomics. Transcription 1(2):76-80
Rando OJ and Winston F (2012) Chromatin and transcription in yeast. Genetics 190(2):351-87
Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38
Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9
Yu H and Gerstein M (2006) Genomic analysis of the hierarchical structure of regulatory networks. Proc Natl Acad Sci U S A 103(40):14724-31
Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Banerjee N and Zhang MQ (2003) Identifying cooperativity among transcription factors controlling the cell cycle in yeast. Nucleic Acids Res 31(23):7024-31
Fillingham J, et al. (2009) Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression. Mol Cell 35(3):340-51
Prather D, et al. (2005) Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae. Mol Cell Biol 25(22):10122-35
Ng HH, et al. (2002) Genome-wide location and regulated recruitment of the RSC nucleosome-remodeling complex. Genes Dev 16(7):806-19
Amin AD, et al. (2013) A global requirement for the HIR complex in the assembly of chromatin. Biochim Biophys Acta 1819(3-4):264-76
McCormick MA and Kennedy BK (2010) Old Yeast Can't Handle the Noise. Mol Cell 39(5):659-61
Tabancay AP Jr and Forsburg SL (2006) Eukaryotic DNA replication in a chromatin context. Curr Top Dev Biol 76():129-84
Lorain S, et al. (1998) Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA. Mol Cell Biol 18(9):5546-56
Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73
Eriksson PR, et al. (2012) Regulation of histone gene expression in budding yeast. Genetics 191(1):7-20
Singh RK, et al. (2009) Generation and management of excess histones during the cell cycle. Front Biosci 14:3145-58
Sutton A, et al. (2001) Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription. Genetics 158(2):587-96
Xu T, et al. (2012) A potent plant-derived antifungal acetylenic acid mediates its activity by interfering with fatty acid homeostasis. Antimicrob Agents Chemother 56(6):2894-907
Lorain S, et al. (1996) Structural Organization of the WD repeat protein-encoding gene HIRA in the DiGeorge syndrome critical region of human chromosome 22. Genome Res 6(1):43-50
Pramila T, et al. (2006) The Forkhead transcription factor Hcm1 regulates chromosome segregation genes and fills the S-phase gap in the transcriptional circuitry of the cell cycle. Genes Dev 20(16):2266-78
Ahmad A, et al. (2005) Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth. J Biol Chem 280(37):32090-100
Qian Z, et al. (1998) Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins. Mol Cell Biol 18(8):4783-92
Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806
Schleker T, et al. (2009) Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. DNA Repair (Amst) 8(9):1089-100
Kurat CF, et al. (2014) Regulation of histone gene transcription in yeast. Cell Mol Life Sci 71(4):599-613
De Lucia F, et al. (2001) Subnuclear localization and mitotic phosphorylation of HIRA, the human homologue of Saccharomyces cerevisiae transcriptional regulators Hir1p/Hir2p. Biochem J 358(Pt 2):447-55
DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67