The 41 papers which experimentally study the biological roles of both TFs of the PCTFP (Pdr3-Yrr1)
Le Crom S, et al. (2002) New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Mol Cell Biol 22(8):2642-9
Salin H, et al. (2008) Structure and properties of transcriptional networks driving selenite stress response in yeasts. BMC Genomics 9:333
Zheng J, et al. (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Jungwirth H and Kuchler K (2006) Yeast ABC transporters-- a tale of sex, stress, drugs and aging. FEBS Lett 580(4):1131-8
Akache B, et al. (2004) Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. J Biol Chem 279(27):27855-60
Srikanth CV, et al. (2005) Acetaminophen toxicity and resistance in the yeast Saccharomyces cerevisiae. Microbiology 151(Pt 1):99-111
Venturi V, et al. (2012) The protein synthesis inhibitors mycalamides A and E have limited susceptibility toward the drug efflux network. J Biochem Mol Toxicol 26(3):94-100
Garcia-Lopez MC, et al. (2010) Overexpression of SNG1 causes 6-azauracil resistance in Saccharomyces cerevisiae. Curr Genet 56(3):251-63
Babbitt GA (2010) Relaxed selection against accidental binding of transcription factors with conserved chromatin contexts. Gene 466(1-2):43-8
Lelandais G and Devaux F (2010) Comparative functional genomics of stress responses in yeasts. OMICS 14(5):501-15
Monteiro PT, et al. (2011) Qualitative modelling and formal verification of the FLR1 gene mancozeb response in Saccharomyces cerevisiae. IET Syst Biol 5(5):308
Akache B and Turcotte B (2002) New regulators of drug sensitivity in the family of yeast zinc cluster proteins. J Biol Chem 277(24):21254-60
MacPherson S, et al. (2006) A fungal family of transcriptional regulators: the zinc cluster proteins. Microbiol Mol Biol Rev 70(3):583-604
Gordan R, et al. (2011) Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol 12(12):R125
Bussereau F, et al. (2006) The Kluyveromyces lactis repertoire of transcriptional regulators. FEMS Yeast Res 6(3):325-35
Teixeira MC, et al. (2008) Yeast adaptation to mancozeb involves the up-regulation of FLR1 under the coordinate control of Yap1, Rpn4, Pdr3, and Yrr1. Biochem Biophys Res Commun 367(2):249-55
Beskow A and Wright AP (2006) Comparative analysis of regulatory transcription factors in Schizosaccharomyces pombe and budding yeasts. Yeast 23(13):929-35
Hazelwood LA, et al. (2010) Involvement of Vacuolar Sequestration and Active Transport in Tolerance of Saccharomyces cerevisiae to Hop Iso-{alpha}-Acids. Appl Environ Microbiol 76(1):318-28
Klein C, et al. (2011) ABC proteins in yeast and fungal pathogens. Essays Biochem 50(1):101-19
Onda M, et al. (2004) Analysis of gene network regulating yeast multidrug resistance by artificial activation of transcription factors: involvement of Pdr3 in salt tolerance. Gene 332():51-9
Teixeira MC, et al. (2012) Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation. Microb Cell Fact 11(1):98
Suzuki T and Iwahashi Y (2012) Comprehensive gene expression analysis of type B trichothecenes. J Agric Food Chem 60(37):9519-27
Nyfeler B, et al. (2012) Identification of elongation factor g as the conserved cellular target of argyrin B. PLoS One 7(9):e42657
Calcada D, et al. (2011) Quantitative modeling of the Saccharomyces cerevisiae flr1 regulatory network using an s-system formalism. J Bioinform Comput Biol 9(5):613-30
Zhao Y, et al. (2008) Development of a Novel Oligonucleotide Array-Based Transcription Factor Assay Platform for Genome-Wide Active Transcription Factor Profiling in Saccharomyces cerevisiae. J Proteome Res 7(3):1315-1325
Shahi P and Moye-Rowley WS (2009) Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi. Biochim Biophys Acta 1794(5):852-9
Jothi R, et al. (2009) Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture. Mol Syst Biol 5:294
Nishida-Aoki N, et al. (2015) Activation of the mitochondrial signaling pathway in response to organic solvent stress in yeast. Curr Genet 61(2):153-164
Galdieri L, et al. (2012) Facilitated assembly of the preinitiation complex by separated tail and head/middle modules of the mediator. J Mol Biol 415(3):464-74
Zhang X, et al. (2001) Cross-talk between transcriptional regulators of multidrug resistance in Saccharomyces cerevisiae. J Biol Chem 276(12):8812-9
Yu H and Gerstein M (2006) Genomic analysis of the hierarchical structure of regulatory networks. Proc Natl Acad Sci U S A 103(40):14724-31
Chanklan R, et al. (2008) Identification of Saccharomyces cerevisiae Tub1 alpha-tubulin as a potential target for NKH-7, a cytotoxic 1-naphthol derivative compound. Biosci Biotechnol Biochem 72(4):1023-31
Butcher RA, et al. (2006) Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. Nat Chem Biol 2(2):103-9
Keeven J, et al. (2002) PDR2 Gain-of-function mutations eliminate the need for Pdr1 and require the UBP6 product for resistance to translational inhibitors. Curr Genet 41(1):11-9
Chinen T, et al. (2011) Construction of multidrug-sensitive yeast with high sporulation efficiency. Biosci Biotechnol Biochem 75(8):1588-93
Cui Z, et al. (1999) Functional analysis of the promoter of the yeast SNQ2 gene encoding a multidrug resistance transporter that confers the resistance to 4-nitroquinoline N-oxide. Biosci Biotechnol Biochem 63(1):162-7
Todd RB and Andrianopoulos A (1997) Evolution of a fungal regulatory gene family: the Zn(II)2Cys6 binuclear cluster DNA binding motif. Fungal Genet Biol 21(3):388-405
Chinen T, et al. (2014) Construction of a genetic analysis-available multidrug sensitive yeast strain by disruption of the drug efflux system and conditional repression of the membrane barrier system. J Gen Appl Microbiol 60(4):160-2
Cui Z, et al. (1998) Yeast gene YRR1, which is required for resistance to 4-nitroquinoline N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2. Mol Microbiol 29(5):1307-15
Teixeira MC, et al. (2010) Refining current knowledge on the yeast FLR1 regulatory network by combined experimental and computational approaches. Mol Biosyst 6(12):2471-81
Morozov AV and Siggia ED (2007) Connecting protein structure with predictions of regulatory sites. Proc Natl Acad Sci U S A 104(17):7068-73