The 114 papers which experimentally study the biological roles of both TFs of the PCTFP (Tec1-Ste12)
Truckses DM, et al. (2004) Jekyll and Hyde in the microbial world. Science 306(5701):1509-11
Chen H and Fink GR (2006) Feedback control of morphogenesis in fungi by aromatic alcohols. Genes Dev 20(9):1150-61
Houser JR, et al. (2012) Positive roles for negative regulators in the mating response of yeast. Mol Syst Biol 8():586
Madhani HD and Fink GR (1998) The control of filamentous differentiation and virulence in fungi. Trends Cell Biol 8(9):348-53
Wong Sak Hoi J and Dumas B (2010) Ste12 and ste12-like proteins, fungal transcription factors regulating development and pathogenicity. Eukaryot Cell 9(4):480-5
Conte D Jr and Curcio MJ (2000) Fus3 controls Ty1 transpositional dormancy through the invasive growth MAPK pathway. Mol Microbiol 35(2):415-27
Patury S, et al. (2009) Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization. Cell Biochem Biophys 53(3):127-34
Haase SB and Wittenberg C (2014) Topology and control of the cell-cycle-regulated transcriptional circuitry. Genetics 196(1):65-90
Saito H (2010) Regulation of cross-talk in yeast MAPK signaling pathways. Curr Opin Microbiol 13(6):677-83
Zeitlinger J, et al. (2003) Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling. Cell 113(3):395-404
Hamel LP, et al. (2012) Mitogen-activated protein kinase signaling in plant-interacting fungi: distinct messages from conserved messengers. Plant Cell 24(4):1327-51
Kyoda K, et al. (2004) DBRF-MEGN method: an algorithm for deducing minimum equivalent gene networks from large-scale gene expression profiles of gene deletion mutants. Bioinformatics 20(16):2662-75
Rutherford JC, et al. (2008) A Mep2-dependent Transcriptional Profile Links Permease Function to Gene Expression during Pseudohyphal Growth in Saccharomyces cerevisiae. Mol Biol Cell 19(7):3028-39
Guldener U, et al. (2004) Characterization of the Saccharomyces cerevisiae Fol1 protein: starvation for C1 carrier induces pseudohyphal growth. Mol Biol Cell 15(8):3811-28
Cullen PJ and Sprague GF Jr (2012) The regulation of filamentous growth in yeast. Genetics 190(1):23-49
Emmert-Streib F and Dehmer M (2009) Predicting cell cycle regulated genes by causal interactions. PLoS One 4(8):e6633
Borneman AR, et al. (2006) Target hub proteins serve as master regulators of development in yeast. Genes Dev 20(4):435-48
Rintala E, et al. (2009) Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. BMC Genomics 10():461
Oehlen L and Cross FR (1998) The mating factor response pathway regulates transcription of TEC1, a gene involved in pseudohyphal differentiation of Saccharomyces cerevisiae. FEBS Lett 429(1):83-8
Lai FJ, et al. (2014) A comprehensive performance evaluation on the prediction results of existing cooperative transcription factors identification algorithms. BMC Syst Biol 8 Suppl 4():S9
Vinod PK and Venkatesh KV (2007) Specificity of MAPK signaling towards FLO11 expression is established by crosstalk from cAMP pathway. Syst Synth Biol 1(2):99-108
Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84
Tisi R, et al. (2014) Yeast as a model for ras signalling. Methods Mol Biol 1120():359-90
Chou S, et al. (2004) Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Cell 119(7):981-90
Babbitt GA (2010) Relaxed selection against accidental binding of transcription factors with conserved chromatin contexts. Gene 466(1-2):43-8
Morillon A, et al. (2000) Activation of the Kss1 invasive-filamentous growth pathway induces Ty1 transcription and retrotransposition in Saccharomyces cerevisiae. Mol Cell Biol 20(15):5766-76
Wang Y, et al. (2009) Sumoylation of transcription factor Tec1 regulates signaling of mitogen-activated protein kinase pathways in yeast. PLoS One 4(10):e7456
Borneman AR, et al. (2007) Divergence of transcription factor binding sites across related yeast species. Science 317(5839):815-9
Louw C, et al. (2010) Regulation of endo-polygalacturonase activity in Saccharomyces cerevisiae. FEMS Yeast Res 10(1):44-57
Wu WS and Li WH (2008) Systematic identification of yeast cell cycle transcription factors using multiple data sources. BMC Bioinformatics 9:522
Ydenberg CA and Rose MD (2008) Yeast mating: a model system for studying cell and nuclear fusion. Methods Mol Biol 475:3-20
Lorenz MC, et al. (2000) Characterization of alcohol-induced filamentous growth in Saccharomyces cerevisiae. Mol Biol Cell 11(1):183-99
Pincus D, et al. (2010) Reagents for investigating MAPK signalling in model yeast species. Yeast 27(7):423-30
Ryan O, et al. (2012) Global gene deletion analysis exploring yeast filamentous growth. Science 337(6100):1353-6
Chou S, et al. (2008) Fus3-triggered Tec1 degradation modulates mating transcriptional output during the pheromone response. Mol Syst Biol 4:212
Borneman AR, et al. (2007) Transcription factor binding site identification in yeast: a comparison of high-density oligonucleotide and PCR-based microarray platforms. Funct Integr Genomics 7(4):335-45
Wu WS, et al. (2006) Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle. BMC Bioinformatics 7(1):421
Rupp S, et al. (1999) MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene. EMBO J 18(5):1257-69
Whitmarsh AJ and Davis RJ (1999) Signal transduction by MAP kinases: regulation by phosphorylation-dependent switches. Sci STKE 1999(1):PE1
Varelas X, et al. (2006) The Cdc34/SCF Ubiquitination Complex Mediates Saccharomyces cerevisiae Cell Wall Integrity. Genetics 174(4):1825-39
Kohler T, et al. (2002) Dual role of the Saccharomyces cerevisiae TEA/ATTS family transcription factor Tec1p in regulation of gene expression and cellular development. Eukaryot Cell 1(5):673-86
Huang GH, et al. (2006) CaMac1, a Candida albicans copper ion-sensing transcription factor, promotes filamentous and invasive growth in Saccharomyces cerevisiae. Acta Biochim Biophys Sin (Shanghai) 38(3):213-7
Sengupta N, et al. (2007) Crosstalk between cAMP-PKA and MAP kinase pathways is a key regulatory design necessary to regulate FLO11 expression. Biophys Chem 125(1):59-71
Miller C, et al. (2011) Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Mol Syst Biol 7():458
Park YU, et al. (2006) Identification of Translational Regulation Target Genes during Filamentous Growth in Saccharomyces cerevisiae: Regulatory Role of Caf20 and Dhh1. Eukaryot Cell 5(12):2120-7
Li H and Johnson AD (2010) Evolution of transcription networks - lessons from yeasts. Curr Biol 20(17):R746-53
Gordan R, et al. (2009) Distinguishing direct versus indirect transcription factor-DNA interactions. Genome Res 19(11):2090-100
Vinod PK and Venkatesh KV (2008) A steady state model for the transcriptional regulation of filamentous growth in Saccharomyces cerevisiae. In Silico Biol 8(3-4):207-22
Raithatha S, et al. (2012) Cdk8 regulates stability of the transcription factor Phd1 to control pseudohyphal differentiation of Saccharomyces cerevisiae. Mol Cell Biol 32(3):664-74
Kim TS, et al. (2003) STA10 repression of STA gene expression is caused by a defective activator, flo8, in Saccharomyces cerevisiae. Curr Genet 44(5):261-7
Kim TS, et al. (2004) Recruitment of the Swi/Snf complex by Ste12-Tec1 promotes Flo8-Mss11-mediated activation of STA1 expression. Mol Cell Biol 24(21):9542-56
Yu H and Gerstein M (2006) Genomic analysis of the hierarchical structure of regulatory networks. Proc Natl Acad Sci U S A 103(40):14724-31
Lu CC, et al. (2008) Extracting transcription factor binding sites from unaligned gene sequences with statistical models. BMC Bioinformatics 9 Suppl 12:S7
Bruckner S and Mosch HU (2012) Choosing the right lifestyle: adhesion and development in Saccharomyces cerevisiae. FEMS Microbiol Rev 36(1):25-58
Narlikar L, et al. (2007) A nucleosome-guided map of transcription factor binding sites in yeast. PLoS Comput Biol 3(11):e215
Mao X, et al. (2009) Functional analysis of ScSwi1 and CaSwi1 in invasive and pseudohyphal growth of Saccharomyces cerevisiae. Acta Biochim Biophys Sin (Shanghai) 41(7):594-602
Lo WS and Dranginis AM (1998) The cell surface flocculin Flo11 is required for pseudohyphae formation and invasion by Saccharomyces cerevisiae. Mol Biol Cell 9(1):161-71
Hao N, et al. (2007) Systems biology analysis of G protein and MAP kinase signaling in yeast. Oncogene 26(22):3254-66
Zhou Z, et al. (2002) [CaSRB9, a novel Candida albicans gene, plays a role in morphogenesis of Saccharomyces cerevisiae] Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 34(3):298-304
Wu X and Jiang YW (2005) Possible integration of upstream signals at Cdc42 in filamentous differentiation of S. cerevisiae. Yeast 22(13):1069-77
Braus GH, et al. (2003) Amino acid starvation and Gcn4p regulate adhesive growth and FLO11 gene expression in Saccharomyces cerevisiae. Mol Biol Cell 14(10):4272-84
Madhani HD and Fink GR (1997) Combinatorial control required for the specificity of yeast MAPK signaling. Science 275(5304):1314-7
Arroyo J, et al. (2011) Functional and genomic analyses of blocked protein O-mannosylation in baker's yeast. Mol Microbiol 79(6):1529-46
Garcia R, et al. (2004) The global transcriptional response to transient cell wall damage in Saccharomyces cerevisiae and its regulation by the cell integrity signaling pathway. J Biol Chem 279(15):15183-95
Wang Y and Dohlman HG (2006) Pheromone-regulated sumoylation of transcription factors that mediate the invasive to mating developmental switch in yeast. J Biol Chem 281(4):1964-9
Yu T and Li KC (2005) Inference of transcriptional regulatory network by two-stage constrained space factor analysis. Bioinformatics 21(21):4033-8
Lelandais G and Devaux F (2010) Comparative functional genomics of stress responses in yeasts. OMICS 14(5):501-15
Song Q and Kumar A (2012) An Overview of Autophagy and Yeast Pseudohyphal Growth: Integration of Signaling Pathways during Nitrogen Stress. Cells 1(3):263-83
Kim HY, et al. (2014) Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11. Biochem Biophys Res Commun 449(2):202-7
Mosch HU, et al. (1999) Crosstalk between the Ras2p-controlled mitogen-activated protein kinase and cAMP pathways during invasive growth of Saccharomyces cerevisiae. Mol Biol Cell 10(5):1325-35
Mayhew D and Mitra RD (2014) Transcription factor regulation and chromosome dynamics during pseudohyphal growth. Mol Biol Cell 25(17):2669-76
Gordan R, et al. (2011) Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol 12(12):R125
Otero JM, et al. (2010) Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications. BMC Genomics 11():723
Lai WK and Buck MJ (2013) An integrative approach to understanding the combinatorial histone code at functional elements. Bioinformatics 29(18):2231-7
Rachfall N, et al. (2013) RACK1/Asc1p, a ribosomal node in cellular signaling. Mol Cell Proteomics 12(1):87-105
Lengeler KB, et al. (2000) Signal transduction cascades regulating fungal development and virulence. Microbiol Mol Biol Rev 64(4):746-85
Chou S, et al. (2006) Regulation of mating and filamentation genes by two distinct Ste12 complexes in Saccharomyces cerevisiae. Mol Cell Biol 26(13):4794-805
Jothi R, et al. (2009) Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture. Mol Syst Biol 5:294
Jones SK Jr and Bennett RJ (2011) Fungal mating pheromones: choreographing the dating game. Fungal Genet Biol 48(7):668-76
Heise B, et al. (2010) The TEA transcription factor Tec1 confers promoter-specific gene regulation by Ste12-dependent and -independent mechanisms. Eukaryot Cell 9(4):514-31
Torma A, et al. (2009) Concordant gene regulation related to perturbations of three GDP-mannose-related genes. FEMS Yeast Res 9(1):63-72
Baur M, et al. (1997) Cooperative binding interactions required for function of the Ty1 sterile responsive element. Mol Cell Biol 17(8):4330-7
Gavrias V, et al. (1996) Saccharomyces cerevisiae TEC1 is required for pseudohyphal growth. Mol Microbiol 19(6):1255-63
Reddy TE, et al. (2007) Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes. Nucleic Acids Res 35(3):e20
Breitkreutz A, et al. (2003) Phenotypic and transcriptional plasticity directed by a yeast mitogen-activated protein kinase network. Genetics 165(3):997-1015
Zanders ED (2000) Gene expression analysis as an aid to the identification of drug targets. Pharmacogenomics 1(4):375-84
Sun W, et al. (2007) Detection of eQTL modules mediated by activity levels of transcription factors. Bioinformatics 23(17):2290-7
Laloux I, et al. (1994) Involvement of SRE element of Ty1 transposon in TEC1-dependent transcriptional activation. Nucleic Acids Res 22(6):999-1005
Ferrezuelo F, et al. (2009) Bck2 is a phase-independent activator of cell cycle-regulated genes in yeast. Cell Cycle 8(2):239-52
Gancedo JM (2001) Control of pseudohyphae formation in Saccharomyces cerevisiae. FEMS Microbiol Rev 25(1):107-23
Elion EA, et al. (2005) Signal transduction. Signaling specificity in yeast. Science 307(5710):687-8
Contador CA, et al. (2011) Identification of transcription factors perturbed by the synthesis of high levels of a foreign protein in yeast saccharomyces cerevisiae. Biotechnol Prog 27(4):925-36
Bester MC, et al. (2012) Many Saccharomyces cerevisiae Cell Wall Protein Encoding Genes Are Coregulated by Mss11, but Cellular Adhesion Phenotypes Appear Only Flo Protein Dependent. G3 (Bethesda) 2(1):131-41
Goh WS, et al. (2010) Blurring of high-resolution data shows that the effect of intrinsic nucleosome occupancy on transcription factor binding is mostly regional, not local. PLoS Comput Biol 6(1):e1000649
Kim TS, et al. (2004) Glucose repression of STA1 expression is mediated by the Nrg1 and Sfl1 repressors and the Srb8-11 complex. Mol Cell Biol 24(17):7695-706
Foster HA, et al. (2013) The Zinc Cluster Protein Sut1 Contributes to Filamentation in Saccharomyces cerevisiae. Eukaryot Cell 12(2):244-53
Pan X and Heitman J (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19(7):4874-87
Chen RE and Thorner J (2007) Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1773(8):1311-40
Granek JA and Magwene PM (2010) Environmental and genetic determinants of colony morphology in yeast. PLoS Genet 6(1):e1000823
Waltermann C and Klipp E (2010) Signal integration in budding yeast. Biochem Soc Trans 38(5):1257-64
de Godoy LM, et al. (2008) Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast. Nature 455(7217):1251-4
Octavio LM, et al. (2009) Epigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expression. PLoS Genet 5(10):e1000673
Gagiano M, et al. (2002) The sensing of nutritional status and the relationship to filamentous growth in Saccharomyces cerevisiae. FEMS Yeast Res 2(4):433-70
Hu B, et al. (2009) Mechanisms and constraints on yeast MAPK signaling specificity. Biophys J 96(12):4755-63
Shock TR, et al. (2009) Hog1 mitogen-activated protein kinase (MAPK) interrupts signal transduction between the Kss1 MAPK and the Tec1 transcription factor to maintain pathway specificity. Eukaryot Cell 8(4):606-16
Gagiano M, et al. (2003) Mss11p is a transcription factor regulating pseudohyphal differentiation, invasive growth and starch metabolism in Saccharomyces cerevisiae in response to nutrient availability. Mol Microbiol 47(1):119-34
Wu WS and Lai FJ (2015) Properly defining the targets of a transcription factor significantly improves the computational identification of cooperative transcription factor pairs in yeast. BMC Genomics 16 Suppl 12():S10
Engelberg D, et al. (2014) Transmembrane signaling in Saccharomyces cerevisiae as a model for signaling in metazoans: state of the art after 25 years. Cell Signal 26(12):2865-78
Cao F and Chen JY (2005) [Cloning and functional study of CaPPe1 in Candida albicans by using Saccharomyses cerevisiae model system] Shi Yan Sheng Wu Xue Bao 38(2):119-25
Tirosh I, et al. (2008) On the relation between promoter divergence and gene expression evolution. Mol Syst Biol 4():159
Wang L, et al. (2012) Integrating phosphorylation network with transcriptional network reveals novel functional relationships. PLoS One 7(3):e33160
Bardwell L (2006) Mechanisms of MAPK signalling specificity. Biochem Soc Trans 34(Pt 5):837-41
van der Felden J, et al. (2014) The Transcription Factors Tec1 and Ste12 Interact with Coregulators Msa1 and Msa2 To Activate Adhesion and Multicellular Development. Mol Cell Biol 34(12):2283-2293
Gustin MC, et al. (1998) MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1264-300